Molecular imaging of atherosclerosis with integrated PET imaging

Molecular imaging of atherosclerosis with integrated PET imaging

Atherosclerotic diseases account for nearly half of all deaths and are leading causes of adult disability. Our understanding of how atherosclerosis leads to cardiovascular disease events has evolved: from a concept of progressive luminal narrowing, to that of sudden rupture and thrombosis of biologically active atheroma. In concert with this conceptual shift, contemporary imaging techniques now...

PET imaging for atherosclerosis

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PET Molecular Targets and Near-Infrared Fluorescence Imaging of Atherosclerosis

PURPOSE OF REVIEW With this review, we aim to summarize the role of positron emission tomography (PET) and near-infrared fluorescence imaging (NIRF) in the detection of atherosclerosis. RECENT FINDINGS 18F-FDG is an established measure of increased macrophage activity. However, due to its low specificity, new radiotracers have emerged for more specific detection of vascular inflammation and o...

4D PET: Beyond conventional dynamic PET imaging

  In this paper, we review novel techniques in the emerging field of spatiotemporal 4D PET imaging. We will discuss existing limitations in conventional dynamic PET imaging which involves independent reconstruction of dynamic PET datasets. Various approaches that seek to attempt some or all of these limitations are reviewed in this work, including techniques that util...

Molecular Imaging and Atherosclerosis